IMPaCT's mission is to establish and transfer the necessary knowledge to support and facilitate the effective deployment of Personalized Precision Medicine, which will represent a paradigm shift and a new reality for the healthcare system, enabling a preventive, diagnostic, and therapeutic approach that is personalized, more effective, and safer for each patient.
Name in original language
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Initiative overview
Spain’s IMPaCT initiative is a national programme, coordinated by the Carlos III Health Institute (Instituto de Salud Carlos III, ISCIII), designed to accelerate the deployment of Personalized Precision Medicine across the Spanish National Health System. It is intended to shift healthcare toward more preventive, diagnostic, and therapeutic approaches that are tailored to each patient, making them safer and more effective.
The structure of IMPaCT is arranged around three major axes or pillars:
- Predictive Medicine (the Cohort Axis): This involves building a large-scale, population-based cohort. The cohort is meant to include 200,000 people from 50 “nodes” spread across all 17 autonomous communities plus Ceuta and Melilla. Participants will provide data via clinical records, lifestyle/environmental inputs, biological sampling and periodic follow-ups.
- Data Science (the DATA Axis): This axis deals with integrating and analysing clinical, molecular and genetic data. It aims to ensure good practices around data collection, interoperability, secondary data use, and building models for research and healthcare decision making.
- Genomic Medicine (the GENOMICS Axis): This pillar supports the genomic-side of things: developing infrastructure to carry out high-complexity genomic analyses, sequencing, and making those resources available across the country.
Two cross-cutting themes run through all of IMPaCT: ethics and scientific integrity, and internationalization.
Name of responsible organisation (in English)
ImPaCT Genomica
